What are
Restylane®
and Perlane®?
The Restylane family of products includes Restylane and Perlane. Both are cosmetic dermal fillers that replace lost volume and restore youthful contours to the skin to smooth away moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).
How do choose between Restylane and Perlane?
You don’t have to. In clinical trials, Restylane and Perlane were used in the same patients. The hyaluronic acid in both products is made by the same biotechnical process. The difference is in the gel particle size. Perlane gel particles are larger and designed for deeper injection than Restylane. Dr. Divers will decide which product is right for you.
How long do Restylane products last?
Restylane products are proven to deliver long-lasting results. Restylane lasts about six months. Perlane lasts at least six months, in a majority of patients. The products’ patented stabilization technology helps maintain the cosmetic effect for those time periods.*
Are Restylane and Perlane FDA approved?
Yes. They are approved by the FDA for the treatment of moderate to severe facial wrinkles and folds, like the ones from your nose to the corners of your mouth. Ask your physician whether treatment is right for you.
What should patients do prior to treatment?
Restylane and Perlane require no pretesting, but you should take a few precautions before being treated. Avoid using aspirin, non-steroidal anti-inflammatory medications, St. John's Wort, or high doses of Vitamin E supplements prior to treatment, because these may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, discuss this with Dr. Divers, who may prescribe a medication to minimize recurrence.
How are Restylane products administered?
Restylane and Perlane are administered by injection to the treatment site. Before treatment talk to Dr. Divers about pain management.
Is any of the material left in the skin after it has dissolved?
No. Over time Restylane and Perlane products are broken down and eliminated by the body—unlike permanent fillers.
Do the injections hurt?
Restylane products are injected directly into the skin in small amounts by an ultrafine needle. As with all injections, some patients may experience discomfort. To increase your comfort, Dr. Divers will assess your need for pain management and determine what technique is right for you.
How much do treatments cost?
A Restylane or Perlane procedure is customized to your specific needs, so the cost will vary. In general, the cost is comparable to the cost of similar procedures. Ask Dr. Divers to give a cost estimate based on your particular needs.
How often should I schedule an appointment?
How long the aesthetic correction lasts is very individual. Talk to Dr. Divers about the benefits of scheduling a follow-up appointment in about six months.
What are Restylane and Perlane products made of?
Restylane was the first cosmetic dermal filler made from hyaluronic acid that has been modified slightly to last longer than the body’s hyaluronic acid. In the human body natural hyaluronic acid provides volume and fullness to the skin.
How do Restylane and Perlane products differ from Botox® Cosmetic?
Botox Cosmetic and Restylane are used to correct wrinkles in different ways. Restylane products are natural, cosmetic fillers injected into the skin, adding volume to smooth wrinkles such as the lines from your nose to the corners of your mouth (nasolabial folds). In contrast, Botox relaxes the muscles that cause frown lines between your eye brows.
*2004 Dermatologist/Plastic Surgeon Awareness, Trial, and Usage Survey
†The American Society for Aesthetic Plastic Surgery
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